WebOct 3, 2012 · We found that TAp63 is important in regulating energy metabolism by accumulating in response to metabolic stress and transcriptionally activating Sirt1, … Webthe various isoforms (TAp63 and ΔNp63 isoforms) of p63 in HCC1806 squamous carcinoma lysate and colon cancer. Precautions 1. For in vitro diagnostic use. 2. For professional users. ... Onboard time is tracked by the Dako Omnis Software. If reagents are stored under any conditions other than those specified, the conditions
The TAp63/BCL2 axis represents a novel mechanism of …
WebApr 11, 2024 · To develop TAp63 and ΔNp63 specific oligonucleotide primers and TaqMan probes optimized for the RT-qPCR system, the National Center for Biotechnology … WebTAp63 is a suppressor of tumorigenesis and metastasis . More aggressive, metastatic tumors lose TAp63 expression, suggesting that loss of TAp63 accelerates tumorigenesis and metastatic spread (1, 5, 9). Delta ... Annexin-V-FITC and 50 μg/ml 7-AAD (7-amino-actinomycin D) prior to FACS analysis. The data were analyzed using FlowJo software ... seventh tap shreveport
MicroRNA-133b is regulated by TAp63 while no gene mutation is …
WebJul 22, 2015 · Ectopic expression or stress-induced accumulation of TAp63 can promote cell cycle arrest and apoptotic cell death through activating p53 pro-apoptotic targets, such as Puma, Bax and p21 [13], [26], [31], [32], [33]. Our data demonstrate that PKCδ-induced accumulation of TAp63 may increase transcription of Bax-luc reporter, and enhance cell ... WebHuman Gene Set: PID_TAP63_PATHWAY. Standard name. PID_TAP63_PATHWAY. Systematic name. M256. Brief description. Validated transcriptional targets of TAp63 isoforms. Full description or abstract. Collection. Webment and maintenance. The TP63 gene encodes two major protein isoforms, TAp63 and DNp63, which have both transactivating and transcriptional repressing activities and … seventh technology