Phosphosulindac
Web1. An isolated IL-23p19 antibody, comprising a light chain variable region and a heavy chain variable region, said light chain variable region comprising:a complementarity determi WebJul 27, 2012 · Phospho-sulindac (P-S, OXT-328), a novel sulindac derivative, has shown superior anticancer efficacy and safety compared to sulindac. In this study, we …
Phosphosulindac
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WebJan 1, 2024 · 1. Introduction. Phospho-sulindac (PS, OXT-328) is a novel agent with anticancer and anti-inflammatory properties. The anti-inflammatory efficacy of topically … Weblow cost. None of the available treatments for DED meets these criteria.Phosphosulindac (PS) is a proprietary compound. We developed novel robust rabbit models of DED encompassing its main pathophysiological subgroups (evaporative, aqueous deficient and mixed). PS showed remarkable efficacy against DED; excellent safety; practically
Webproposing to develop a novel compound, phosphosulindac, which is potentially a highly effective and safe agent. The expected results will pave the way towards the completion … WebSulindac (Fig. 5 A) is a non-steroidal anti-inflammatory drug used to treat inflammatory diseases such as rheumatoid arthritis and osteoarthritis. 27 Mass balance studies using radiolabeled sulindac in humans have demonstrated that sulindac is extensively and rapidly absorbed after oral administration; ~ 90% of the dose is absorbed, and the …
Webtherapeutic effect of the novel anti-inflammatory drug phosphosulindac (PS) in rabbit models of DED en-compassing its pathogenesis, and its transition to chronicity. Methods: … WebNational Center for Biotechnology Information
WebApis Therapeutics, LLC Location: USA Founded in 2011 "The treatment of dry eye disease using pharmacological agents is suboptimal and new agents are urgently needed. Apis Therapeutics is aiming to develop a novel compound, phosphosulindac, which is potentially a highly effective and safe agent.
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