Phosphopantetheine attachment site
WebNov 13, 2013 · 4ihh: Chasing acyl carrier protein through a catalytic cycle of lipid A production. WebMar 23, 2024 · It has 12 putative transmembrane domains and intracellular N and C termini. SLC26A1 contains a sulfate transporter signature, a phosphopantetheine attachment site, …
Phosphopantetheine attachment site
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WebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are … WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process / acyl binding / lipid binding / phosphopantetheine binding Processes fatty acid biosynthetic process / lipid A biosynthetic process / lipid biosynthetic process / response to drug Components cytoplasm / cytosol General Function
WebApr 26, 2024 · In addition, it showed a close relationship with the phosphopantetheine attachment site protein (IPR006162) and acyl carrier protein of super family SSF47336 (IPR009081). It also shares similarities with the peptide chains of IPR020806 polyketide synthase, phosphopantetheine-binding domain, and others including IPR020845, … WebJan 17, 2024 · Among the 7 domains, the acyltransferase domain and phosphopantetheine attachment site showed the highest number of hydrogen bonds with gallic acid, i.e., 7/6 and 3/1 in hexanoic acid, respectively. According to our findings, gallic acid has a stronger binding affinity in these two domains than hexanoic acid since GA needs less binding …
WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins ... which forms the 4′PPan cofactor attachment site. This α-helical region as well as two other α-helical segments (helix 1, residues 3–15 and helix 4, ... WebOct 1, 2024 · Genome sequencing, comparative genomic analysis, and gene disruption of Streptomycessp. SYP-A7193 showed that the inthomycin biosynthetic gene cluster (itm) belonged to the hybrid polyketide synthase (PKS)/nonribosomal peptide …
WebJan 10, 2024 · To obtain active CAR enzyme, a phosphopantetheine group must be attached covalently to a conserved serine in the PCP domain mediated by a suitable …
WebThe human NDUFAB1 protein contains a phosphopantetheine attachment site (DLGLDSLDQVEIIMAM), unique for acyl carrier proteins, and an EF-hand calcium binding … cshbtht-st3w-m6-35WebPromotional Article Monitoring. Register your specific details and specific drugs of interest and we will match the information you provide to articles from our extensive database and email PDF copies to you promptly. eagan family dentistry reviewsWebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ... cshbtht-st3w-m8-15Phosphopantetheine, also known as 4'-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). It is also present in formyltetrahydrofolate dehydrogenase. cshbtht-st3w-m5-12WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Alternate IDs None Definition Binding an acyl group and presenting it for processing or … eagan fastpitchWebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Definition: Interacting selectively and non-covalently with the attachment site of the … eagan field statusWebJul 17, 2024 · The PCP Ser702, which serves as the phosphopantetheine attachment site, is positioned 52 Å away from the bound AMP phosphate. By contrast, ... cshbtht-st3w-m6-30