WebApr 3, 2007 · The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT ( PubMed: 15525651 ). WebProtein tyrosine phosphorylation is a key regulatory mechanism in eukaryotic cell physiology. Aberrant expression or function of protein tyrosine kinases and protein tyrosine phosphatases can lead to serious human diseases, including cancer, diabetes, as well as cardiovascular, infectious, autoimmune, and neuropsychiatric disorders.
EGR2 phosphatase regulates OST1 kinase activity and …
WebGO:0017020 myosin phosphatase regulator activity GO:0072542 protein phosphatase activator activity GO:0004864 protein phosphatase inhibitor activity Parents of protein phosphatase regulator activity (GO:0019888) Children of protein phosphatase regulator activity (GO:0019888) Reactome R-HSA-180038 Cite this data• Terms of use• GO helpdesk http://amigo.geneontology.org/amigo/term/GO:0019208 chiropractic pillow amazon
Category:GO:0019888 ! protein phosphatase regulator activity
WebPHACTR1. Phosphatase and actin regulator 1 (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. [5] It is most significantly expressed in the globus pallidus of the brain. [6] PHACTR1 is an actin and protein phosphatase 1 (PP1) binding protein that binds actin and regulates the reorganization of the actin ... WebThe nonreceptor protein-tyrosine phosphatase (PTP) SHP2 is encoded by the proto-oncogene PTPN11 and is a ubiquitously expressed key regulator of cell signaling, acting on a number of cellular ... WebAll were found to be mutations in the catalytic domain of ABI1 and lacked a detectable phosphatase activity in in vitro assays. Since they were loss-of-function mutations, it could be concluded that ABI1 phosphatase acts as a negative regulator of ABA responses. The exact manner in which the ABI1 phosphatase attenuates the ABA signal is unknown ... chiropractic physiotherapy defined