Cytoskeleton-associated protein 4
WebMar 21, 2024 · Cytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is expressed … WebOct 25, 2010 · Deep sequencing of mutant DNA revealed a mutation located in an intron of the Mtap2 gene, encoding microtubule-associated protein 2, and levels of Mtap2 transcript were reduced in mutant testes. ... Together, these and other as yet unknown regulators bring about progressive changes in the nucleus and cytoskeleton, including desynapsis, ...
Cytoskeleton-associated protein 4
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WebJul 21, 2024 · Since then, various components of the cytoskeleton network have been shown to be involved in virtually all steps of the viral life cycle. For example, numerous viruses have been found to re-organize actin structures near the plasma membrane to facilitate endocytosis-mediated viral entry [ 2, 3, 4 ]. Once inside the cell, many viruses … WebSep 4, 2009 · Palladin is an actin cytoskeleton–associated protein which is crucial for cell morphogenesis and motility. Previous studies have shown that palladin is localized to the axonal growth cone in neurons and may play an important role in axonal extension. Previously, we have generated palladin knockout mice which display cranial neural tube …
WebEdges represent protein-protein associations associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other. Known Interactions from curated databases experimentally determined Predicted Interactions gene neighborhood gene fusions WebCiliary Proteins Primary Cilium Proteome Database This database shows proteins identified in primary cilia of mouse IMCD3 cells, compiled from three different proteomic publications: 1. Biochemical isolation using calcium-shock. Ishikawa, H., Thompson, J., Yates III, J. R., & Marshall, W. F. (2012). Proteomic Analysis of Mammalian Primary Cilia.
CKAP4 as a receptor of APF plays an important role in mediating bladder carcinoma cells proliferation. Following CKAP4 knockdown, the inhibition effect of APF on T24 cell proliferation was eliminated, indicating the important role of the receptor in mediating the antiproliferation activity of APF in bladder cancer … See more Our group investigated the relationship between CKAP4/DHHC2 expression and prognosis in 416 patients with hepatocellular carcinoma (HCC) (Li et al., 2014b) (Table 2). … See more Previous studies reported that CKAP4 as an ER enriched protein could be secreted by exosomes of ovarian and colon cancer cells and detected as an exosomal protein in urine (Gonzales et al., 2009; Demory Beckler et al., 2013; … See more Although plentiful researches focused on the relationship between CKAP4 and cancer, there were also studies that showed that CKAP4 played an important role in noncancers. … See more Sufficient studies have confirmed that CKAP4 correlated with various cancers’ progress and prognosis. The formation of the xenograft tumors derived from CKAP4-depleted cells, including lung cancer cells (Kimura et al., 2016), … See more WebJul 8, 2024 · Synaptic activity mediates information storage and memory consolidation in the brain and requires a fast de novo synthesis of mRNAs in the nucleus and proteins in synapses. Intracellular localization of a protein can be achieved by mRNA trafficking and localized translation. Activity-regulated cytoskeleton-associated protein (Arc) is a …
WebMay 17, 2024 · CKAP4 (cytoskeleton‐associated protein 4) is a DKK1 binding protein expressed on the surface of cells, with DKK1/CKAP4 promoting pancreatic cancer and lung cancer . DKK1 is considered a factor that can modulate the β‐catenin pathway and stimulate cancer cells or noncancerous proliferation [61, 62]. Zyxin localizes to focal adhesion sites ...
WebFeb 25, 2024 · They applied it for the first time to the intestine and identified regenerating islet-derived protein 4 ( Reg4) as a novel marker for enteroendocrine cells, a rare population of hormone-producing intestinal cells [ 32 ]. Regenerative properties of the adult mammalian heart are insufficient to repair the heart post-ischemic injury. ctb bandWebJan 8, 2024 · Suggest a role for cytoskeleton-associated protein 4 in modulating fibroblast activation in the injured heart. CLIMP-63 (also known as CKAP4), is the partner of triadin, is responsible for this association of triads and microtubules. p63 positively regulates desmosome adhesion by directly controlling the expression of several desmosome genes ... earrings for sensitive ears kidsWebMar 21, 2024 · Cytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is expressed primarily in the plasma membranes of bladder epithelial cells, type II alveolar pneumocytes, and vascular smooth muscle cells. earrings for round faceWebAppropriate cytoskeletal organization is essential for vascular smooth muscle cell (VSMC) conditions such as hypertension. This study identifies FXR1 … earrings for sensitive ears studsWebCytoskeleton-associated protein 4 (CKAP4) also called as p63 is a 63kDa protein, which belongs to the family of type II transmembrane receptor. This membrane protein consists of NH2 terminus with 106-amino acid-long cytosolic tail and a transmembrane domain and an extracytoplasmic domain of 474 aa at the COOH terminus. [ 1] [ 2] Immunogen earrings for sensitive ears walmartWebCytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma. Background: Recent years have witnessed significant … ctb belfortWebFeb 22, 2014 · Cytoskeleton-associated membrane protein 4 (CKAP4), also known as P63, with a molecular weight 63 kilodaltons, is a type of type II transmembrane protein that is located in the endoplasmic reticulum. 3, … ctb battery