WebDec 1, 2024 · Re: Cisplatin vs Transplatin. The cis-chlorine arrangement on cisplatin (the two chlorines are on the same side of the central atom) is what allows it to bind as … WebMay 11, 2011 · Analysis of the energetic and structural parameters of cisplatin vs. transplatin behavior in the model systems leads to conclusion: there are two possible ways of cisplatin biotransformation, hydrolysis and hydrated electron impact, dependent on the medium redox state. Introduction
Cisplatin vs. Transplatin - What
WebOct 1, 1988 · The clonogenic assay failed to discriminate between highly active in vivo antitumor agents and analogues with only marginal in vivo efficacy (i.e., doxorubicin and daunorubicin versus rhodomycins A and B, ametantrone versus NSC 276740, cisplatin versus transplatin, [Au(dppe)2]Cl versus [Au(depe)2]PF6. WebThe results showed that higher concentrations of the cis isomer were localized in the liver and kidney, while the concentration of the trans isomer was higher in blood. This indicates that trans isomer is sequestered in the central compartment, whereas cis isomer is distributed in the organs. orchidfix nursery
Interactions of cisplatin and transplatin with proteins ... - PubMed
WebTransplatin, (an isomer of cisplatin that has the chlorine atoms opposite each other, rather than on the same side) also forms adducts with DNA, but mostly mono-adducts. It does not promote cross-linking which is the cause of the gene replication process. The cisplatin molecule binds with a protein on one side and the DNA molecule on the other. WebAug 8, 2024 · Perbedaan utama antara cisplatin dan transplatin adalah bahwa cisplatin menghasilkan lebih banyak penculikan DNA daripada transplatin. Cisplatin penting sebagai obat antikanker, sedangkan transplatin tidak memiliki efek pengobatan yang penting. Apa Perbedaan Utama Antara Sastra Kolonial dan Postkolonial John Stephens … orchidex afff 6% ul