WebAug 2, 2024 · In people who take high doses of methotrexate, there might be a buildup of the drug in the bloodstream, potentially causing an overdose. Research shows at least 1.8% of people who use methotrexate experience some type of kidney dysfunction. 12 Methotrexate (Rheumatrex) Side Effects Cyclosporine WebFeb 21, 2024 · Symptoms can include: trouble breathing chest pain fever or chills rash or itchy skin Abnormal heart rhythm. Symptoms can include: fast, slow, or fluttering heart rate a pounding feeling in...
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